Definition of "screwed"

screwed

adjective
comparative more screwed, superlative most screwed
1. (slang, mildly vulgar) Beset with unfortunate circumstances that seem difficult or impossible to overcome; in imminent danger.
2. (slang, Britain, dated) Intoxicated.
  Quotations
  " […] Did you know that my husband came home intoxicated?"Mrs. Brown laughed."Oh, not so bad as that, surely! Only a little 'screwed.' George was 'quisby,' too. But then its Christmas, you know."
  1889, Belgravia, volume 70, page 15
  Besides they were dreadfully afraid that Freddy Malins might turn up screwed. They would not wish for worlds that any of Mary Jane's pupils should see him under the influence […]
  1914 June, James Joyce, “The Dead”, in Dubliners, London: Grant Richards
verb
1. simple past and past participle of screw
  Quotations
  […] merchants are in no part of the world so screwed as in England. In Turkey, they have more encouragement.
  1641, Richard Chambers (merchant), quoted in Hannis Taylor, The Origin and Growth of the English Constitution: An Historical Treatise, Part II: The After-Growth of the Constitution, H.O. Houghton & Company (1889), p. 274