Definition of "annihilate"

annihilate

/əˈnaɪə.leɪt/

verb
third-person singular simple present annihilates, present participle annihilating, simple past and past participle annihilated
1. To reduce to nothing, to destroy, to eradicate.
  Quotations
  But eagerness in this case, as in most others, annihilated its own delight; down came the tottering height, while the disappointed builder found relief for his sorrow in anger—sorrow's best remedy after all.
  1834, L[etitia] E[lizabeth] L[andon], chapter XXII, in Francesca Carrara. […], volume II, London: Richard Bentley, […], (successor to Henry Colburn), page 237
2. (particle physics) To react with antimatter, producing gamma radiation and (for higher-mass reactants, especially composite particles such as protons) lighter particles (such as pions, muons, and neutrinos).
3. (archaic) To treat as worthless, to vilify.
  Quotations
  of all the opinions which Antiquity hath had of men in gross, those which I most willingly embrace, and whereon I take most hold, are such as most vilifie, condemne, and annihilate us.
  1603, Michel de Montaigne, chapter 17, in John Florio, transl., The Essayes […], book II, London: […] Val[entine] Simmes for Edward Blount […]
4. (transitive) To render null and void; to abrogate.