Definition of "depletion"

The act of depleting, or the state of being depleted; exhaustion.  examples

The consumption of a resource faster than it can be replenished.  examples

(medicine, archaic) The act of relieving congestion or plethora, by purging, blood-letting, or reduction of the system by abstinence.

(accounting, mining, timber, petroleum) gradual expense or use of natural resources over time.  examples