Definition of "handed"

As poisonous tongued as handed

1611 April (first recorded performance), William Shakespeare, “The Tragedie of Cymbeline”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […] (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, [Act III, scene ii]

yet now, if any two be but once handed in the Church, and have tasted in any sort the nuptiall bed, let them finde themselves never so mistak’n in their dispositions through any error, concealment, or misadventure, that through their different tempers, thoughts, and constitutions, they can neither be to one another a remedy against lonelines, nor live in any union or contentment all their dayes, yet they shall, so they be but found suitably weapon’d to the least possibility of sensuall enjoyment, be made, spight of antipathy to fadge together, and combine as they may to their unspeakable wearisomnes and despaire of all sociable delight in the ordinance which God establisht to that very end.

1643, John Milton, Doctrine and Discipline of Divorce

Into their inmost bower, / Handed they went.

1667, John Milton, “Book IV”, in Paradise Lost. […], London: […] [Samuel Simmons], […]; republished as Paradise Lost in Ten Books: […], London: Basil Montagu Pickering […], 1873,